What have we learned from basic science studies on idiopathic pulmonary fibrosis?

Toyoshi Yanagihara, Seidai Sato, Chandak Upagupta, Martin Kolb

研究成果: ジャーナルへの寄稿総説査読

35 被引用数 (Scopus)

抄録

Idiopathic pulmonary fibrosis is a fatal age-related lung disease characterised by progressive and irreversible scarring of the lung. Although the details are not fully understood, there has been tremendous progress in understanding the pathogenesis of idiopathic pulmonary fibrosis, which has led to the identification of many new potential therapeutic targets. In this review we discuss several of these advances with a focus on genetic susceptibility and cellular senescence primarily affecting epithelial cells, activation of profibrotic pathways, disease-enhancing fibrogenic cell types and the role of the remodelled extracellular matrix.

本文言語英語
論文番号190029
ジャーナルEuropean Respiratory Review
28
153
DOI
出版ステータス出版済み - 9月 30 2019
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 呼吸器内科

フィンガープリント

「What have we learned from basic science studies on idiopathic pulmonary fibrosis?」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル