Tuned cell attachments by double-network hydrogels consisting of glycol chitosan, carboxylmethyl cellulose and agar bearing robust and self-healing properties

Ik Sung Cho, Tooru Ooya

研究成果: ジャーナルへの寄稿学術誌査読

12 被引用数 (Scopus)

抄録

Herein we present a tuned cell attachment on self-healable double network hydrogel bearing dynamic covalent bonds and hydrogen bonds. Agar formed first network, while glycol chitosan and oxidized carboxylmethyl cellulose formed second network in the resultant double network hydrogel. Because of the simple one-pot preparation, the hydrogel can be injected by using syringes. The moduli of the hydrogel were improved compared to that of the parent single-network. The hydrogel exhibited self-healing ability without need for heating or cut surface treatment. The incorporation of agar in the double network induced the enhanced protein adsorption, and the following cell attachments were governed by the adsorbed protein states. Therefore, the double network hydrogel holds great potential for applications in various biomedical applications.

本文言語英語
ページ(範囲)262-268
ページ数7
ジャーナルInternational Journal of Biological Macromolecules
134
DOI
出版ステータス出版済み - 8月 1 2019
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 構造生物学
  • 生化学
  • 分子生物学
  • 経済学、計量経済学
  • エネルギー一般

フィンガープリント

「Tuned cell attachments by double-network hydrogels consisting of glycol chitosan, carboxylmethyl cellulose and agar bearing robust and self-healing properties」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル