TY - GEN
T1 - Thermally tunable deterministic lateral displacement through hydrogel micro pillar arrays
AU - Tottori, N.
AU - Sakurai, Y.
AU - Nisisako, T.
AU - Yanagida, Y.
AU - Hatsuzawa, T.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - We present a novel deterministic lateral displacement (DLD) microfluidic device with thermally tunable separation capability. To flexibly change the critical diameter (Dc) of the separation array, we fabricated DLD micropillars made of poly-N-isopropylacrylamide, a thermo-responsive hydrogel, in a polydimethyl siloxane microfluidic channel. The prepared DLD pillars shrunk at a high temperature (>30°C) and swelled at a low temperature (<30°C) in an aqueous solution because of their characteristic hydrophilic-hydrophobic phase transitions. By heating and cooling the DLD device across the transition temperature, the Dccould be continuously changed and the separation mode of the model particles could be switched.
AB - We present a novel deterministic lateral displacement (DLD) microfluidic device with thermally tunable separation capability. To flexibly change the critical diameter (Dc) of the separation array, we fabricated DLD micropillars made of poly-N-isopropylacrylamide, a thermo-responsive hydrogel, in a polydimethyl siloxane microfluidic channel. The prepared DLD pillars shrunk at a high temperature (>30°C) and swelled at a low temperature (<30°C) in an aqueous solution because of their characteristic hydrophilic-hydrophobic phase transitions. By heating and cooling the DLD device across the transition temperature, the Dccould be continuously changed and the separation mode of the model particles could be switched.
UR - http://www.scopus.com/inward/record.url?scp=85014178908&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85014178908&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85014178908
T3 - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
SP - 140
EP - 141
BT - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PB - Chemical and Biological Microsystems Society
T2 - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Y2 - 9 October 2016 through 13 October 2016
ER -