The self-assembled monolayer of saccharide via click chemistry: Formation and protein recognition

Yoshiko Miura, Takahiro Yamauchi, Hajime Sato, Tomohiro Fukuda

研究成果: ジャーナルへの寄稿学術誌査読

29 被引用数 (Scopus)

抄録

We prepared the saccharide-immobilized substrate via click chemistry. The azide-terminated saccharides were reacted by a facile metathesis reaction. The density of saccharides was controlled by the incubation time of SAM preparation. The saccharide-protein interaction was analyzed using the saccharide substrate. The interaction of the saccharide substrate with protein was strong and specific due to the glyco-cluster effects. The interaction with amyloid β was analyzed by the monosaccharide-immobilized substrate, and the sulfonated saccharides showed strong interaction.

本文言語英語
ページ(範囲)2443-2449
ページ数7
ジャーナルThin Solid Films
516
9
DOI
出版ステータス出版済み - 3月 3 2008
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 電子材料、光学材料、および磁性材料
  • 表面および界面
  • 表面、皮膜および薄膜
  • 金属および合金
  • 材料化学

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