To identify the possible mechanism of wheeze generationin the tracheostenosis, we measured the inspiratory andexpiratory flow in the realistic model reconstructed based onCT data of patient. Trachea consists of tracheal cartilage ringsand smooth muscle, which influence the localized variation ofdistensibility of model airway. The localized variation ofdistensibility was achieved by the varied thickness of siliconerubber based on the elastic modulus measured for the pigairway. The Reynolds number was 1100, and both inspiratoryand expiratory flow were disturbed by the stenosis. Theturbulence intensity for the distensible model is moderatedcompared the rigid model.