Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate

Masaharu Murata; Wataru Kaku; Takahisa Anada; Yoshikuni Sato; Mizuo Maeda; Yoshiki Katayama

doi:10.1246/cl.2003.986

Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate

Masaharu Murata
, Wataru Kaku
, Takahisa Anada
, Yoshikuni Sato
, Mizuo Maeda
, Yoshiki Katayama

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

10 被引用数 (Scopus)

抄録

We prepared a novel antisense reagent comprising of oligodeoxynucleotides (ODNs) and a thermo-responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm). The conjugate demonstrated stimuli-responsive regulation of gene expression via conformational change of the polymer chain.

本文言語	英語
ページ（範囲）	986-987
ページ数	2
ジャーナル	Chemistry Letters
巻	32
号	11
DOI	https://doi.org/10.1246/cl.2003.986
出版ステータス	出版済み - 11月 5 2003

!!!All Science Journal Classification (ASJC) codes

化学一般

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10.1246/cl.2003.986

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title = "Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate",

abstract = "We prepared a novel antisense reagent comprising of oligodeoxynucleotides (ODNs) and a thermo-responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm). The conjugate demonstrated stimuli-responsive regulation of gene expression via conformational change of the polymer chain.",

author = "Masaharu Murata and Wataru Kaku and Takahisa Anada and Yoshikuni Sato and Mizuo Maeda and Yoshiki Katayama",

year = "2003",

month = nov,

day = "5",

doi = "10.1246/cl.2003.986",

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journal = "Chemistry Letters",

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T1 - Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate

AU - Murata, Masaharu

AU - Kaku, Wataru

AU - Anada, Takahisa

AU - Sato, Yoshikuni

AU - Maeda, Mizuo

AU - Katayama, Yoshiki

PY - 2003/11/5

Y1 - 2003/11/5

N2 - We prepared a novel antisense reagent comprising of oligodeoxynucleotides (ODNs) and a thermo-responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm). The conjugate demonstrated stimuli-responsive regulation of gene expression via conformational change of the polymer chain.

AB - We prepared a novel antisense reagent comprising of oligodeoxynucleotides (ODNs) and a thermo-responsive polymer, poly(N-isopropylacrylamide) (PNIPAAm). The conjugate demonstrated stimuli-responsive regulation of gene expression via conformational change of the polymer chain.

UR - https://www.scopus.com/pages/publications/0842263697

UR - https://www.scopus.com/pages/publications/0842263697#tab=citedBy

U2 - 10.1246/cl.2003.986

DO - 10.1246/cl.2003.986

M3 - Article

AN - SCOPUS:0842263697

SN - 0366-7022

VL - 32

SP - 986

EP - 987

JO - Chemistry Letters

JF - Chemistry Letters

IS - 11

ER -

Temperature-dependent Regulation of Antisense Activity Using a DNA/poly(N-isopropylacrylamide) Conjugate

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!!!All Science Journal Classification (ASJC) codes

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