Synchronized Chiral Induction between [5]Helicene–Spermine Ligand and B–Z DNA Transition

Kensuke Kawara, Genichiro Tsuji, Yosuke Taniguchi, Shigeki Sasaki

研究成果: ジャーナルへの寄稿学術誌査読

15 被引用数 (Scopus)

抄録

The 2,13-dimethoxy[5]helicene–spermine ligand 8 b possesses an axial chirality. The racemic 8 b was bound to B-DNA by the accompanying induction of its (P)-chirality together with the B-to-Z helicity change of the duplex DNA, [(dC-dG)3]2. The (P)-chirality of the bound 8 b, in turn, transitioned to the (M)-chirality according to the Z-helicity of the DNA. These results illustrate the chirality synchronization between the DNA and the ligand.

本文言語英語
ページ(範囲)1763-1769
ページ数7
ジャーナルChemistry - A European Journal
23
8
DOI
出版ステータス出版済み - 2月 3 2017

!!!All Science Journal Classification (ASJC) codes

  • 触媒
  • 有機化学

フィンガープリント

「Synchronized Chiral Induction between [5]Helicene–Spermine Ligand and B–Z DNA Transition」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル