Surgical strategy for advanced gallbladder carcinoma according to invasive depth of the tumor

Yuji Morine, Mitsuo Shimada, Satoru Imura, Masahiko Fujii, Tetsuya Ikemoto, Yuji Soejima, Toru Utsunomiya, Nobuhiro Kurita, Hidenori Miyake, Seiki Tashiro

研究成果: ジャーナルへの寄稿学術誌査読

3 被引用数 (Scopus)

抄録

Background/Aims: The postoperative survival rate is dependent on the invasive depth of the gallbladder carcinoma. When this carcinoma has invaded beyond the subserosal layer, lymph node and adjacent organ involvement is found in a large number of patients, and long-term survival cannot be achieved. The aim of this study is to establish a surgical strategy for advanced gallbladder carcinoma according to the invasive depth. Methodology: A retrospective analysis was conducted of 44 patients with the gallblader carcinoma. The invasive depth was histologically defined by the Japanese Society of Biliary Surgery system as follows. (hinf0: within muscle layer, hinfla:subserosal layer, hinf1b; hepatic infiltration within 5 mm, hinf2.3: hepatic infiltration more than 5 mm) Results: Wedge resection of the gallbladder bed was performed in 5 cases, and in four of the five patients (80%), intrahepatic recurrence occurred within 6 months. S4a+S5 subsegmentectomy of the liver is performed in 11 cases (hinf0,1a/b:n=5, hinf2,3:n=6) and the postoperative survival rate was significantly better in cases of hinf0,1a/b (p<0.05). In cases of hinf2,3 an extended hepatic lobectomy (n=5) tended to obtain a better survival rate, compared with S4a+S5 subsegmentectomy (n=6)(p=0.13). Conclusions: S4a+S5 subsegmentectomy of the liver is a standard operation for GB carcinoma with subserosal invasion.

本文言語英語
ページ(範囲)1965-1970
ページ数6
ジャーナルHepato-gastroenterology
55
88
出版ステータス出版済み - 11月 2008
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 消化器病学
  • 肝臓学

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