A study was conducted to demonstrate surface modification of stereoregular and stereocomplex poly(methyl methacrylate) (PMMA) films with biologically identified material-binding peptides (MBP). Isotactic (it)- and syndiotactic (st)-PMMA film surfaces were modified with biotinylated peptides that specifically bound to the polymers and analyzed the binding of streptavidin (SAv) to these immobilized peptides. PMMA stereocomplex (SC) films, which were composed of it- and st-PMMAs, were evaluated by their specific peptides under the same conditions and the results were compared against those of it- and st-PMMAs. The static contact angle of PMMA films on gold-coated glass slides was measured with a commercial apparatus. The surface topology of the PMMA films was visualized by non-contact mode atomic force microscopy (AFM) in air using a silicon cantilever.
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