TY - JOUR
T1 - Streptococcal toxic shock syndrome due to Streptococcus dysgalactiae subsp. equisimilis from retroperitoneal panniculitis during the treatment with anti-IL-6 receptor antibody
T2 - A case report
AU - Fujimoto, Sho
AU - Eriguchi, Yoshihiro
AU - Nakamura, Rinto
AU - Kamikawa, Sota
AU - Yonekawa, Akiko
AU - Miyake, Noriko
AU - Ono, Nobuyuki
AU - Niiro, Hiroaki
N1 - Publisher Copyright:
© Japan College of Rheumatology 2024. Published by Oxford University Press. All rights reserved.
PY - 2024/7/1
Y1 - 2024/7/1
N2 - A 53-year-old man with adult-onset Still’s disease developed severe streptococcal toxic shock syndrome (STSS) due to Streptococcus dysgalactiae subsp. equisimilis (SDSE), following retroperitoneal panniculitis. He was receiving tocilizumab (TCZ), an interleukin-6 receptor inhibitor. The modifying effect of TCZ on the immune response and the pathophysiology of SDSE infection may have led to retroperitoneal panniculitis and atypical STSS with delayed shock and flare of soft tissue inflammation.
AB - A 53-year-old man with adult-onset Still’s disease developed severe streptococcal toxic shock syndrome (STSS) due to Streptococcus dysgalactiae subsp. equisimilis (SDSE), following retroperitoneal panniculitis. He was receiving tocilizumab (TCZ), an interleukin-6 receptor inhibitor. The modifying effect of TCZ on the immune response and the pathophysiology of SDSE infection may have led to retroperitoneal panniculitis and atypical STSS with delayed shock and flare of soft tissue inflammation.
KW - Streptococcal toxic shock syndrome
KW - streptococcus dysgalactiae subsp. equisimilis
KW - tocilizumab
KW - β-hemolytic streptococcus
UR - http://www.scopus.com/inward/record.url?scp=85198245426&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85198245426&partnerID=8YFLogxK
U2 - 10.1093/mrcr/rxae001
DO - 10.1093/mrcr/rxae001
M3 - Article
C2 - 38217091
AN - SCOPUS:85198245426
SN - 2472-5625
VL - 8
SP - 255
EP - 258
JO - Modern Rheumatology Case Reports
JF - Modern Rheumatology Case Reports
IS - 2
ER -