Social withdrawal in major depressive disorder: a case-control study of hikikomori in japan

Alan R. Teo, Sarah Nelson, Wynn Strange, Hiroaki Kubo, Ryoko Katsuki, Keita Kurahara, Shigenobu Kanba, Takahiro A. Kato

研究成果: ジャーナルへの寄稿学術誌査読

26 被引用数 (Scopus)


Background: Social withdrawal is a feature of a number of psychiatric disorders including major depressive disorder (MDD), yet research examining social withdrawal as a feature of MDD is rare. Methods: This was a retrospective case-control study. Participants (N = 67) were recruited through an outpatient clinic at an academic medical center in Japan. Major depressive disorder (MDD) and social withdrawal were established with the Structured Clinical Interview for DSM-IV Axis I Disorders and a semi-structured psychiatric interview, respectively. Participants also completed self-report measures. Results: We classified 24 participants as cases (MDD with social withdrawal) and 43 participants as controls (MDD without social withdrawal). Cases, on average, were more likely to have lower education level, prior episodes of depression, and higher suicidal ideation at baseline than controls. In unadjusted regression models, cases had significantly less social connection, less reward dependence, less self-directedness, and higher scores on scales of modern-type depression and hikikomori. In adjusted regression models, associations between social withdrawal and hikikomori (p<0.01) and reward dependence (p = 0.03) remained significant. Limitations: The sample was limited in size and drawn from a single site. Conclusions: In patients with MDD, social withdrawal may have subtle associations with clinical symptoms, social connection, and personality traits. Developing a better understanding of social withdrawal's phenotype in depression requires more in-depth examination.

ジャーナルJournal of Affective Disorders
出版ステータス出版済み - 9月 1 2020

!!!All Science Journal Classification (ASJC) codes

  • 臨床心理学
  • 精神医学および精神衛生


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