Selective protein adsorption property and structure of "nano- crystalline hydroxy-carbonate apatite

S. Hayakawa, K. Ohnishi, K. Tsuru, A. Osaka, E. Fujii, K. Kawabata, F. Babonneau, C. Bonhomme

研究成果: ジャーナルへの寄稿学術誌査読

13 被引用数 (Scopus)

抄録

The selective protein adsorption property and the local structure around carbonate ions of nanocrystalline hydroxy-carbonate apatite were examined in this study. Considerable change in the selectivity in the adsorption of BSA and β2-MG was observed due to the incorporation of the carbonate ions in hydroxyapatite lattice. Since the protein adsorption property seems to be related to the surface charge density of hydroxyapatite due to the carbonation, the chemical states of the incorporated carbonate ions were examined by the 31C CP-MAS NMR spectroscopy. At least four peaks assignable to carbonate ions in A-site(OH-) and B-site(PO 43-) were observed in 13C CP-MAS NMR spectrum. Thus, we must take into consideration that the surface charge distribution and the decrement of polar groups such as OH- groups due to the distribution of carbonate ions in both A- and B-sites of the hydroxyapatite lattice are particularly favorable for β2-MG adsorption rather than for BSA adsorption.

本文言語英語
ページ(範囲)503-506
ページ数4
ジャーナルKey Engineering Materials
309-311 I
DOI
出版ステータス出版済み - 2006
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 材料科学一般
  • 材料力学
  • 機械工学

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