Sampling and quality assurance

For the efficient operation of clinical laboratories, automated biochemical analyzers have been improved. Large rapidly analyzing and multichannel analyzers, and small or mid-sized multiple component analyzers are now commercially available and widely use. Such apparatus might require only a small amount of specimen and reagent to assay one analyte. Performance has been increased annually. In this report, we discuss whether this performance, sampling of specimen, sampling of reagent, and mixing effect of reaction mixture or diluted specimen affect the accuracy and precision of measurements.