TY - CHAP
T1 - Review
T2 - The regulation of tooth development and morphogenesis
AU - Nakamura, Takashi
AU - Yamada, Yoshihiko
AU - Fukumoto, Satoshi
N1 - Publisher Copyright:
© Springer 2012.
PY - 2012/1/1
Y1 - 2012/1/1
N2 - A variety of vertebrate organs, including teeth, begins their development by inductive sequential and reciprocal interactions between epithelium and mesenchyme. In tooth development, the interactions between ectodermal-derived epithelium and the cranial neural crest-derived mesenchyme regulate the shape, position, and size of the tooth crown with a functional cusp. During tooth development, many signaling molecules and transcription factors regulate tooth development and morphogenesis. Recently, we reported Epiprofin, an Sp transcription factor, is expressed during tooth development and exerts critical roles in dental epithelial differentiation and the determination of tooth number. In this review, we describe the expression pattern and functions of Epiprofin in tooth development.
AB - A variety of vertebrate organs, including teeth, begins their development by inductive sequential and reciprocal interactions between epithelium and mesenchyme. In tooth development, the interactions between ectodermal-derived epithelium and the cranial neural crest-derived mesenchyme regulate the shape, position, and size of the tooth crown with a functional cusp. During tooth development, many signaling molecules and transcription factors regulate tooth development and morphogenesis. Recently, we reported Epiprofin, an Sp transcription factor, is expressed during tooth development and exerts critical roles in dental epithelial differentiation and the determination of tooth number. In this review, we describe the expression pattern and functions of Epiprofin in tooth development.
UR - http://www.scopus.com/inward/record.url?scp=84935038114&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84935038114&partnerID=8YFLogxK
U2 - 10.1007/978-4-431-54070-0_3
DO - 10.1007/978-4-431-54070-0_3
M3 - Chapter
AN - SCOPUS:84935038114
SN - 9784431540694
SP - 14
EP - 21
BT - Interface Oral Health Science 2011
PB - Springer Japan
ER -