Response to osteoblastic cells of bioactive organic-inorganic hybrid

Y. Aburatani, T. Uchida, Y. Shirosaki, K. Tsuru, S. Hayakawa, A. Osaka

研究成果: ジャーナルへの寄稿会議記事査読

1 被引用数 (Scopus)


Organically modified silicate gels were synthesized starting from ploy(dimethylsiloxane), tetraethoxysilane, calcium nitrate, and colloidal silica through sol-gel processing. In vitro apatite deposition on the colloidal silica containing hybrids in a simulated body fluid of the Kokubo recipe was confirmed, indicating they were bioactive. Cell proliferation for the hybrid gels with the colloidal silica was better than the colloidal silica free gels. The cells cultured for 7 days on the hybrid gels with colloidal silica expanded their pseudopodium and were well attached. In contrast, the cells were hardly observable on the colloidal silica free gels. Thus, the hybrids with colloidal silica are cytocompatible as well as bioactive.

ジャーナルKey Engineering Materials
出版ステータス出版済み - 2003
イベントProceedings of the 15th International Symposium on Ceramics in Medicine; The Annual Meeting of the International Society for Ceramics in Medicine - Sydney, NSW, オーストラリア
継続期間: 12月 4 200212月 8 2002

!!!All Science Journal Classification (ASJC) codes

  • 材料科学一般
  • 材料力学
  • 機械工学


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