Prognostic value of the histological subtype in completely resected non-small cell lung cancer

Tatsuro Okamoto, Riichiroh Maruyama, Ryuichi Suemitsu, Yoshiro Aoki, Hiroshi Wataya, Miyako Kojo, Yukito Ichinose

研究成果: ジャーナルへの寄稿学術誌査読

14 被引用数 (Scopus)

抄録

Non-small cell lung cancer (NSCLC), which includes several different histological subtypes, is usually treated by the same strategy. However, the biological behavior of each cell type appears to be different. We retrospectively reviewed the clinical records of 1119 consecutive NSCLC patients who underwent a complete resection, in order to investigate whether a histological cell type is a powerful prognostic factor. The overall 5- and 10-year survivals of the patients with adenocarcinoma (AD), squamous cell carcinoma (SQ), large cell carcinoma (LA), and adenosquamous cell carcinoma (AS) were 54.2 and 40.2%, 51.6 and 30.3%, 40.9 and 18.7%, and 35.1 and 30.1%, respectively. The AD patients had a significantly better survival than the non-AD patients in Stage I (P = 0.0004), whereas the SQ patients had a better survival than the non-SQ patients in Stage II (P = 0.018). A multivariate survival analysis indicated the AD patients to have a significantly better survival than the SQ patients in Stage IA (P = 0.04), while the SQ patients had a better survival than the AD patients in Stage II (P = 0.03). These above observations suggest that the prognosis after complete resection is different between adenocarcinoma and squamous cell carcinoma in Stage IA and II.

本文言語英語
ページ(範囲)362-366
ページ数5
ジャーナルInteractive cardiovascular and thoracic surgery
5
4
DOI
出版ステータス出版済み - 8月 1 2006
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 外科
  • 呼吸器内科
  • 循環器および心血管医学

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