Oral administration of chicken breast extract activates serotonin metabolism in the hippocampus of rats

Shozo Tomonaga, Mikako Sato, Yoshihisa Takahata, Fumiki Morimatsu, Mitsuhiro Furuse

研究成果: ジャーナルへの寄稿学術誌査読

2 被引用数 (Scopus)

抄録

We previously reported that Chicken Breast Extract (CBEX) had an antidepressant-like effect in rats. In the present study to further clarify, the mechanism of action of CBEX, the effects of CBEX on the brain serotonin (5-HT) system was investigated mthe ventral hippocampus of rats, using an in vivo micro dialysis. 5-Hydroxyindoleacetic acid, a major metabolite of serotonin, was significantly increased in animals orally administered CBEX. This result indicates that CBEX may activate 5-HT metabolism in the brain. Since, a previous study indicated that orally administered CBEX increases levels of the putative neurotransmitter carnosine in the hippocampus, carnosine might be involved in the action of CBEX.

本文言語英語
ページ(範囲)2276-2279
ページ数4
ジャーナルJournal of Animal and Veterinary Advances
8
11
出版ステータス出版済み - 2009

!!!All Science Journal Classification (ASJC) codes

  • 農業および作物学
  • 獣医学一般

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