抄録
On the substrate carrying a sub-wavelength grating covered with a thin metal layer, a fluorescent dye-labeled cell was observed by fluorescence microscope. The fluorescence intensity was more than 20 times greater than that on an optically flat glass substrate. Such a great fluorescence enhancement from labeled cells bound to the grating substrate was due to the excitation by grating coupled surface plasmon resonance. The application of a grating substrate to two-dimensional detection and fluorescence microscopy appears to offer a promising method of taking highly sensitive fluorescence images.
| 本文言語 | 英語 |
|---|---|
| ページ（範囲） | 9781-9790 |
| ページ数 | 10 |
| ジャーナル | Optics Express |
| 巻 | 16 |
| 号 | 13 |
| DOI | |
| 出版ステータス | 出版済み - 6月 23 2008 |
| 外部発表 | はい |
!!!All Science Journal Classification (ASJC) codes
- 原子分子物理学および光学