TY - JOUR
T1 - Optical coherence tomography angiography of choroidal neovascularization in immune choroiditis following acute retinal necrosis
AU - Nakamura, Shun
AU - Nakao, Shintaro
AU - Shiose, Satomi
AU - Kohno, Ri Ichiro
AU - Hasegawa, Eiichi
AU - Sonoda, Koh Hei
N1 - Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by grants from JSPS KAKENHI, Grant-in-Aid for Scientific Research (C) No. 17K11456 (SN) and No. 20K09829 (SN), Charitable Trust Fund for Ophthalmic Research in Commemoration of Santen Pharmaceutical’s Founder (SN), Novartis Pharma Research Grants (SN), Alcon Pharma Research Grants (SN), and Takeda Science Foundation (SN)
Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by grants from JSPS KAKENHI, Grant-in-Aid for Scientific Research (C) No. 17K11456 (SN) and No. 20K09829 (SN), Charitable Trust Fund for Ophthalmic Research in Commemoration of Santen Pharmaceutical?s Founder (SN), Novartis Pharma Research Grants (SN), Alcon Pharma Research Grants (SN), and Takeda Science Foundation (SN)
Publisher Copyright:
© The Author(s) 2020.
PY - 2022/1
Y1 - 2022/1
N2 - Purpose: To report optical coherence tomography angiography (OCTA) findings in a case of immune choroiditis following contralateral acute retinal necrosis (ARN) with choroidal neovascularization (CNV) during anti-vascular endothelial growth factor (VEGF) therapy. Case report: A 64-year-old woman with immune choroiditis following contralateral ARN and secondary CNV presented with decreased visual acuity. Fundus examination revealed macular and peripheral yellowish lesions in the right eye. Inflammatory cells were observed in the anterior chamber and the vitreous. OCT revealed retinal exudative changes and subretinal lesions suggestive of CNV. OCTA detected an abnormal vascular net in the outer retina as well as choriocapillaris, corresponding to type 2 CNV, that reduced following intravitreous anti-VEGF therapy. Two weeks after treatment, OCTA showed re-dilated choroidal neovasculature at the outer retina despite no exudative recurrence in OCT. Six weeks after treatment, OCT detected exudative changes around the neovascular lesion. Conclusion: This case discusses the use of OCTA detection of CNV in a case of immune choroiditis following contralateral ARN. During anti-VEGF therapy for inflammatory CNV-related diseases, OCTA may be useful not only for CNV detection but also for the follow-up of CNV activity.
AB - Purpose: To report optical coherence tomography angiography (OCTA) findings in a case of immune choroiditis following contralateral acute retinal necrosis (ARN) with choroidal neovascularization (CNV) during anti-vascular endothelial growth factor (VEGF) therapy. Case report: A 64-year-old woman with immune choroiditis following contralateral ARN and secondary CNV presented with decreased visual acuity. Fundus examination revealed macular and peripheral yellowish lesions in the right eye. Inflammatory cells were observed in the anterior chamber and the vitreous. OCT revealed retinal exudative changes and subretinal lesions suggestive of CNV. OCTA detected an abnormal vascular net in the outer retina as well as choriocapillaris, corresponding to type 2 CNV, that reduced following intravitreous anti-VEGF therapy. Two weeks after treatment, OCTA showed re-dilated choroidal neovasculature at the outer retina despite no exudative recurrence in OCT. Six weeks after treatment, OCT detected exudative changes around the neovascular lesion. Conclusion: This case discusses the use of OCTA detection of CNV in a case of immune choroiditis following contralateral ARN. During anti-VEGF therapy for inflammatory CNV-related diseases, OCTA may be useful not only for CNV detection but also for the follow-up of CNV activity.
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U2 - 10.1177/1120672120977349
DO - 10.1177/1120672120977349
M3 - Article
C2 - 33246374
AN - SCOPUS:85096870432
SN - 1120-6721
VL - 32
SP - NP114-NP118
JO - European Journal of Ophthalmology
JF - European Journal of Ophthalmology
IS - 1
ER -