Noncurative resection for advanced gastric cancer

Yoshihiko Maehara, Yoshihiro Kakeji, Ikuo Takahashi, Toshiro Okuyama, Hideo Baba, Hideaki Anai, Keizo Sugimachi

研究成果: ジャーナルへの寄稿学術誌査読

12 被引用数 (Scopus)


Between 1965 and 1985, 489 patients with advanced gastric cancer who were treated with gastric resection and in whom tumor cells remained after the operation were defined as cases of a “noncurative resection.” The clinicopathological features and prognosis of these patients were examined and two groups were prepared: locally advanced cancer and cancer with a distant metastasis. In locally advanced cancer cases, tumor cells remained in the neighboring organs, lymph nodes, and/or resected margins; in those with distant metastasis, peritoneal dissemination and/or liver metastasis were present regardless of whether or not the metastasis was removed, with or without locally noncurative factors. Serosal invasion was prominent and high rates of lymph node metastasis and lymphatic inolvement were evident in both groups. The survival rate for patients with locally advanced gastric cancer was better than that of patients with distant metastasis (P < 0.01). Survival time in patients with locally advanced cancer can be lengthened by resecting all of the primary tumor and as much of the metastatic lesions as possible, even if the surgical management is “noncurative.” Aggressive postoperative chemotherapy for patients with distant metastasis from a gastric cancer is to be recommended. © 1992 Wiley‐Liss, Inc.

ジャーナルJournal of Surgical Oncology
出版ステータス出版済み - 12月 1992

!!!All Science Journal Classification (ASJC) codes

  • 外科
  • 腫瘍学


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