TY - GEN
T1 - Nanowires enabling cancer diagnosis from 1 mL urine
AU - Naganawa, Tsuyoshi
AU - Yasui, Takao
AU - Yanagida, Takeshi
AU - Kaji, Noritada
AU - Kanai, Masaki
AU - Nagashima, Kazuki
AU - Kawai, Tomoji
AU - Baba, Yoshinobu
PY - 2020/1/1
Y1 - 2020/1/1
N2 - We have far developed the device with ZnO nanowires for in-situ miRNA collection from 1 mL urine. Here, we collected 48 miRNA samples from 24 healthy subjects and 24 cancer subjects. And then, we conducted two kinds of analisis: heatmap and AUC (Area Under the Curve) analysis. After the analysis, we could show the results that miRNA types are different between before and after cancer formation, and that some biomarker candidates were identified. This methodology will be expected to be a pioneer for the new cancer diagnosis from non-invasive miRNA analysis.
AB - We have far developed the device with ZnO nanowires for in-situ miRNA collection from 1 mL urine. Here, we collected 48 miRNA samples from 24 healthy subjects and 24 cancer subjects. And then, we conducted two kinds of analisis: heatmap and AUC (Area Under the Curve) analysis. After the analysis, we could show the results that miRNA types are different between before and after cancer formation, and that some biomarker candidates were identified. This methodology will be expected to be a pioneer for the new cancer diagnosis from non-invasive miRNA analysis.
UR - http://www.scopus.com/inward/record.url?scp=85079665994&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85079665994&partnerID=8YFLogxK
M3 - Conference contribution
T3 - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
SP - 1271
EP - 1272
BT - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PB - Chemical and Biological Microsystems Society
T2 - 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
Y2 - 22 October 2017 through 26 October 2017
ER -