TY - GEN
T1 - Nanowire devices for extracellular vesicles analysis towards elucidation of intercellular communication
AU - Tabuchi, Keiko
AU - Yasui, Takao
AU - Yong, He
AU - Yanagida, Takeshi
AU - Kaji, Noritada
AU - Kanai, Masaki
AU - Nagashima, Kazuki
AU - Kawai, Tomoji
AU - Baba, Yoshinobu
PY - 2015
Y1 - 2015
N2 - We fabricate ZnO nanowires inside microchannels on Si substrates. Since the ZnO nanowires have positively charged surface [1] and most vesicles have negatively charged surface, it is able to capture the vesicles on the nanowire surface by electrostatic interaction. MicroRNA is extracted from the captured vesicles by introducing lysis buffer. It is expected that our fabricate devices would lead to fundamental understanding of cell-cell communication.
AB - We fabricate ZnO nanowires inside microchannels on Si substrates. Since the ZnO nanowires have positively charged surface [1] and most vesicles have negatively charged surface, it is able to capture the vesicles on the nanowire surface by electrostatic interaction. MicroRNA is extracted from the captured vesicles by introducing lysis buffer. It is expected that our fabricate devices would lead to fundamental understanding of cell-cell communication.
UR - http://www.scopus.com/inward/record.url?scp=84983335944&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84983335944&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84983335944
T3 - MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 1510
EP - 1512
BT - MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Y2 - 25 October 2015 through 29 October 2015
ER -