Meisetz, a novel histone tri-methyltransferase, regulates meiosis-specific epigenesis

Katsuhiko Hayashi, Yasuhisa Matsui

研究成果: ジャーナルへの寄稿総説査読

41 被引用数 (Scopus)

抄録

Meiosis is a specialized cell division that is essential to reduce the ploidy of the genome and to generate genomic diversity in all sexually reproducing organisms. Our recent investigation revealed that the meiosis-specific histone methyltransferase Meisetz (Meiosis-induced factor containing PR/SET domain and zinc-finger motif) played an essential role on proper progression of meiotic prophase in mouse germ cell lineage. The finding also suggests that the germ cell lineage has a meiosis-specific epigenetic status that is different from that of the somatic cell lineage. This article reviews the function of Meisetz and prospects the epigenetic background allowing proper progression of meiosis in mouse germ cells.

本文言語英語
ページ(範囲)615-620
ページ数6
ジャーナルCell Cycle
5
6
DOI
出版ステータス出版済み - 3月 16 2006
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 分子生物学
  • 発生生物学
  • 細胞生物学

フィンガープリント

「Meisetz, a novel histone tri-methyltransferase, regulates meiosis-specific epigenesis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル