TY - JOUR
T1 - Life Course Epidemiology of Hip Osteoarthritis in Japan
T2 - A Multicenter, Cross-Sectional Study
AU - Sato, Taishi
AU - Yamate, Satoshi
AU - Utsunomiya, Takeshi
AU - Inaba, Yutaka
AU - Ike, Hiroyuki
AU - Kinoshita, Koichi
AU - Doi, Kenichiro
AU - Kawano, Tsutomu
AU - Shiomoto, Kyohei
AU - Hara, Toshihiko
AU - Sonoda, Kazuhiko
AU - Kaneuji, Ayumi
AU - Takahashi, Eiji
AU - Shimizu, Tomohiro
AU - Takahashi, Daisuke
AU - Kohno, Yusuke
AU - Kabata, Tamon
AU - Inoue, Daisuke
AU - Matsuda, Shuichi
AU - Goto, Koji
AU - Mawatari, Taro
AU - Baba, Shoji
AU - Takagi, Michiaki
AU - Ito, Juji
AU - Nakashima, Yasuharu
AU - Yamaguchi, Ryosuke
AU - Motomura, Goro
AU - Hamai, Satoshi
AU - Kawahara, Shinya
AU - Hara, Daisuke
AU - Choe, Hyonmin
AU - Yamamoto, Takuaki
AU - Seo, Hajime
AU - Matsunaga, Taiki
AU - Shin, Satoshi
AU - Fukui, Makoto
AU - Ichiseki, Toru
AU - Kuroda, Yutaka
AU - Kawai, Toshiyuki
AU - Okuzu, Yaichiro
AU - Kawano, Koichiro
AU - Sueda, Reima
AU - Hagio, Satoshi
AU - Harada, Satoru
AU - Takakubo, Yuya
AU - Sameshima, Takeshi
N1 - Publisher Copyright:
© 2024 Lippincott Williams and Wilkins. All rights reserved.
PY - 2024/6/5
Y1 - 2024/6/5
N2 - Background:The incidence of developmental dysplasia of the hip (DDH) in Japanese newborns has reduced drastically following a primary prevention campaign initiated around 1972 to 1973; this perinatal education campaign promoted maintaining the hips of newborns in the naturally flexed-leg position. The purpose of the present study was to describe the life course epidemiology of hip osteoarthritis (OA) in adolescent and adult patients and to assess its association with exposure to the primary prevention campaign for DDH.Methods:We included new patients with hip OA diagnosed from January 1, 2022, to December 31, 2022, at 12 core hospitals (8 special-function hospitals and 4 regional medical care support hospitals). The trend in the percentage of hips with a history of DDH treatment in childhood was estimated with use of a centered moving average using the birth year of the patient. We compared the prevalence of severe subluxation (Crowe type II, III, or IV) between patients with secondary hip OA due to hip dysplasia who were born in or before 1972 and those who were born in or after 1973.Results:Overall, 1,095 patients (1,381 hips) were included. The mean age at the time of the survey was 63.5 years (range, 15 to 95 years). A total of 795 patients (1,019 hips; 73.8% of hips) were diagnosed with secondary OA due to hip dysplasia. Approximately 13% to 15% of hips among patients born from 1963 to 1972 had a history of DDH treatment in childhood; however, the percentage decreased among patients born in or after 1973. The prevalence of severe subluxation (Crowe type II, III, or IV) among patients born in or after 1973 was 2.4%, which was significantly less than that among patients born in or before 1972 (11.1%; odds ratio, 0.20; p < 0.001).Conclusions:As of 2022, secondary hip OA due to hip dysplasia is still responsible for most new cases of adolescent and adult hip OA seen in core hospitals in Japan. However, the perinatal education campaign initiated 50 years ago, which utilized a population approach and advocated for maintaining the hips of newborns in the naturally flexed-leg position, may have improved the environmental factors of DDH, as indicated by the apparently reduced need for treatment of DDH in childhood and the associated severe subluxation. This may result in a reduced need for challenging hip surgery later in life.Level of Evidence:Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
AB - Background:The incidence of developmental dysplasia of the hip (DDH) in Japanese newborns has reduced drastically following a primary prevention campaign initiated around 1972 to 1973; this perinatal education campaign promoted maintaining the hips of newborns in the naturally flexed-leg position. The purpose of the present study was to describe the life course epidemiology of hip osteoarthritis (OA) in adolescent and adult patients and to assess its association with exposure to the primary prevention campaign for DDH.Methods:We included new patients with hip OA diagnosed from January 1, 2022, to December 31, 2022, at 12 core hospitals (8 special-function hospitals and 4 regional medical care support hospitals). The trend in the percentage of hips with a history of DDH treatment in childhood was estimated with use of a centered moving average using the birth year of the patient. We compared the prevalence of severe subluxation (Crowe type II, III, or IV) between patients with secondary hip OA due to hip dysplasia who were born in or before 1972 and those who were born in or after 1973.Results:Overall, 1,095 patients (1,381 hips) were included. The mean age at the time of the survey was 63.5 years (range, 15 to 95 years). A total of 795 patients (1,019 hips; 73.8% of hips) were diagnosed with secondary OA due to hip dysplasia. Approximately 13% to 15% of hips among patients born from 1963 to 1972 had a history of DDH treatment in childhood; however, the percentage decreased among patients born in or after 1973. The prevalence of severe subluxation (Crowe type II, III, or IV) among patients born in or after 1973 was 2.4%, which was significantly less than that among patients born in or before 1972 (11.1%; odds ratio, 0.20; p < 0.001).Conclusions:As of 2022, secondary hip OA due to hip dysplasia is still responsible for most new cases of adolescent and adult hip OA seen in core hospitals in Japan. However, the perinatal education campaign initiated 50 years ago, which utilized a population approach and advocated for maintaining the hips of newborns in the naturally flexed-leg position, may have improved the environmental factors of DDH, as indicated by the apparently reduced need for treatment of DDH in childhood and the associated severe subluxation. This may result in a reduced need for challenging hip surgery later in life.Level of Evidence:Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
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U2 - 10.2106/JBJS.23.01044
DO - 10.2106/JBJS.23.01044
M3 - Article
C2 - 38626018
AN - SCOPUS:85195329577
SN - 0021-9355
VL - 106
SP - 966
EP - 975
JO - Journal of Bone and Joint Surgery
JF - Journal of Bone and Joint Surgery
IS - 11
ER -