Left ventricular performance in aortic valve replacement

Yoshihisa Tanoue, Taketoshi Maeda, Shinichiro Oda, Hironori Baba, Yasuhisa Oishi, Shigehiko Tokunaga, Atsuhiro Nakashima, Ryuji Tominaga

研究成果: ジャーナルへの寄稿学術誌査読

16 被引用数 (Scopus)


We analyzed the mid-term left ventricular (LV) performance after aortic valve replacement (AVR). We measured LV contractility (endsystolic elastance: Ees), afterload (effective arterial elastance: Ea) and efficiency (ventriculoarterial coupling: Ea/Ees; ratio of stroke work and pressure-volume area: SW/PVA) based on transthoracic echocardiography data obtained before, after and approximately 1 year after isolated AVR in 263 patients with aortic stenosis (AS group; n=116), aortic regurgitation (AR group; n=93) or aortic stenosis and regurgitation (ASR group; n=54). The LV volume was calculated by the Teichholz M-mode method. Ees and Ea were approximated as follows: Eessmean blood pressure/minimal LV volume; Ea=systolic blood pressure/(maximal LV volume-minimal LV volume). Thereafter, Ea/Ees and SW/PVA were calculated. Arterial blood pressure was measured using manchette methods. Ees and Ea decreased after AVR inthe AS group, but increased in the AR group. Ea/Ees and SW/PVA worsened after AVR in the AR group, but improved during a 1-year period after AVR in all groups. Contrasting effects of AVR on LV contractility and afterload between AS and AR were clearly demonstrated. The mid-term LV contractility and efficiency after AVR were excellent and satisfactory. However, LV efficiency worsened early after AVR in AR patients.

ジャーナルInteractive cardiovascular and thoracic surgery
出版ステータス出版済み - 8月 2009

!!!All Science Journal Classification (ASJC) codes

  • 外科
  • 呼吸器内科
  • 循環器および心血管医学


「Left ventricular performance in aortic valve replacement」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。