Isolation of rat mitochondrial transcription factor A (r-Tfam) cDNA

Hidetoshi Inagaki, Toshihiko Hayashi, Yuichi Matsushima, Kong Hua Lin, Sumio Maeda, Shigeyuki Ichihara, Yasuo Kitagawa, Takao Saito

研究成果: ジャーナルへの寄稿学術誌査読

25 被引用数 (Scopus)

抄録

We have isolated rat mitochondrial transcription factor A (Tfam; formerly known as mtTFA) cDNA clones from a rat cerebellum cDNA library using human Tfam cDNA as a probe. The deduced amino acid sequence of r-Tfam shows 62% and 89% overall identity to human and mouse Tfam, respectively. We also show the presence of two r-Tfam isoforms in testis as for mouse. Our findings suggest that the mechanisms underlying transcription of mitochondrial genes are conserved among rat, mouse, and human.

本文言語英語
ページ(範囲)131-135
ページ数5
ジャーナルMitochondrial DNA
11
1-2
DOI
出版ステータス出版済み - 2000
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 分子生物学
  • 遺伝学

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