Involvement of deoxyadenosine and adenosine deaminase in the methotrexate-induced suppression of inflammatory bone destruction

Biochemistry, Genetics and Molecular Biology

• Methotrexate 100%
• Adenosine Deaminase 66%
• Deoxyadenosine 66%
• Rat 55%
• Bone 33%
• Adenosine 27%
• Osteoclastogenesis 27%
• Protein 11%
• Bone Marrow Culture 11%
• RANKL 11%
• Western Blot 11%
• Osteoprotegerin 11%
• Adenosine Receptor 11%
• Messenger RNA 5%
• Lysozyme 5%
• Metabolic Pathway 5%
• Molecule 5%
• DNA Synthesis 5%
• Low Drug Dose 5%
• Immunocompetent Cell 5%
• Reverse Transcription Polymerase Chain Reaction 5%
• Nomenclature 5%
• Inosine 5%
• RANK 5%
• Dihydrofolate Reductase 5%
• Tartrate-Resistant Acid Phosphatase 5%
• Antifolate 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Methotrexate 100%
• Adenosine Deaminase 66%
• Deoxyadenosine 66%
• Rat 55%
• Adenosine 27%
• Bone Destruction 27%
• Inflammation 11%
• Protein 11%
• Osteoclast Differentiation Factor 11%
• Osteoprotegerin 11%
• Adenosine Receptor 11%
• Messenger RNA 5%
• Antagonist 5%
• Malignant Neoplasm 5%
• Ligand 5%
• Enzyme 5%
• Receptor 5%
• Neoplasm 5%
• DNA 5%
• Acid Phosphatase Tartrate Resistant Isoenzyme 5%
• Nucleic Acid 5%
• Caffeine 5%
• Dihydrofolate Reductase 5%
• Freund Adjuvant 5%
• Inosine 5%
• Deoxyinosine 5%
• Folic Acid Antagonist 5%
• Antirheumatic Agent 5%