抄録
Isoprenoid-substituted flavonoids were isolated from the wood of Artocarpus heterophyllus by means of activity-guided fractionation. Artocarpin (1), cudraflavone C (2), 6-prenylapigenin (3), kuwanon C (4), norartocarpin (5) and albanin A (6) inhibited melanin biosynthesis in B16 melanoma cells without inhibiting tyrosinase. A structure-activity investigation indicated that the presence of the isoprenoid-substituted moiety enhanced the inhibitory activity on melanin production in B16 melanoma cells.
| 本文言語 | 英語 |
|---|---|
| ページ（範囲） | 847-850 |
| ページ数 | 4 |
| ジャーナル | Planta medica |
| 巻 | 72 |
| 号 | 9 |
| DOI | |
| 出版ステータス | 出版済み - 7月 2006 |
!!!All Science Journal Classification (ASJC) codes
- 分析化学
- 分子医療
- 薬理学
- 薬科学
- 創薬
- 補完代替医療
- 有機化学