Implantable CMOS image sensor with a neural amplifier for simultaneous recording of optical and electrophysiological signals

Kenji Sugie; Kiyotaka Sasagawa; Yasumi Ohta; Hironari Takehara; Makito Haruta; Hiroyuki Tashiro; Jun Ohta

doi:10.1109/BioCAS49922.2021.9644940

Implantable CMOS image sensor with a neural amplifier for simultaneous recording of optical and electrophysiological signals

Kenji Sugie
, Kiyotaka Sasagawa
, Yasumi Ohta
, Hironari Takehara
, Makito Haruta
, Hiroyuki Tashiro
, Jun Ohta

研究成果: 書籍/レポートタイプへの寄稿 › 会議への寄与

4 被引用数 (Scopus)

抄録

In this work, we developed an implantable device for simultaneous optical observation and electrophysiological recording. The prototype image sensor was designed using a 0.35-m standard complementary metal-oxide-semiconductor process, and green fluorescent protein fluorescence imaging of mouse brain slices was performed using the image sensor. In addition, a neural amplifier integrated on the same chip to amplify the weak neural signals obtained a midband gain of 39 dB at 40 mHz-3 kHz, and the input-referred noise was 4.9 Vrms. Crosstalk of the image sensor clock signal observed in the neural amplifier output was reduced using a software filter.

本文言語	英語
ホスト出版物のタイトル	BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings
出版社	Institute of Electrical and Electronics Engineers Inc.
ISBN（電子版）	9781728172040
DOI	https://doi.org/10.1109/BioCAS49922.2021.9644940
出版ステータス	出版済み - 2021
外部発表	はい
イベント	2021 IEEE Biomedical Circuits and Systems Conference, BioCAS 2021 - Virtual, Online, ドイツ継続期間: 10月 6 2021 → 10月 9 2021

出版物シリーズ

名前	BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings

会議

会議	2021 IEEE Biomedical Circuits and Systems Conference, BioCAS 2021
国/地域	ドイツ
City	Virtual, Online
Period	10/6/21 → 10/9/21

!!!All Science Journal Classification (ASJC) codes

ハードウェアとアーキテクチャ
生体医工学
電子工学および電気工学

文献へのアクセス

10.1109/BioCAS49922.2021.9644940

他のファイルとリンク

フィンガープリント

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引用スタイル

Sugie, K., Sasagawa, K., Ohta, Y., Takehara, H., Haruta, M., Tashiro, H., & Ohta, J. (2021). Implantable CMOS image sensor with a neural amplifier for simultaneous recording of optical and electrophysiological signals. In BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings (BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BioCAS49922.2021.9644940

Implantable CMOS image sensor with a neural amplifier for simultaneous recording of optical and electrophysiological signals. / Sugie, Kenji; Sasagawa, Kiyotaka; Ohta, Yasumi その他.
BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings. Institute of Electrical and Electronics Engineers Inc., 2021. (BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings).

研究成果: 書籍/レポートタイプへの寄稿 › 会議への寄与

Sugie, K, Sasagawa, K, Ohta, Y, Takehara, H, Haruta, M, Tashiro, H & Ohta, J 2021, Implantable CMOS image sensor with a neural amplifier for simultaneous recording of optical and electrophysiological signals. in BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings. BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings, Institute of Electrical and Electronics Engineers Inc., 2021 IEEE Biomedical Circuits and Systems Conference, BioCAS 2021, Virtual, Online, ドイツ, 10/6/21. https://doi.org/10.1109/BioCAS49922.2021.9644940

Sugie K, Sasagawa K, Ohta Y, Takehara H, Haruta M, Tashiro H その他. Implantable CMOS image sensor with a neural amplifier for simultaneous recording of optical and electrophysiological signals. In BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings. Institute of Electrical and Electronics Engineers Inc. 2021. (BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings). doi: 10.1109/BioCAS49922.2021.9644940

Sugie, Kenji ; Sasagawa, Kiyotaka ; Ohta, Yasumi その他. / Implantable CMOS image sensor with a neural amplifier for simultaneous recording of optical and electrophysiological signals. BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings. Institute of Electrical and Electronics Engineers Inc., 2021. (BioCAS 2021 - IEEE Biomedical Circuits and Systems Conference, Proceedings).

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