Impaired glucose tolerance and insulin resistance in chronic calcifying pancreatitis

K. Ogoshi, I. Nakano, T. Ito, T. Miyahara, S. Koyanagi, Y. Migita, N. Sekiguchi, F. Ueda, H. Nawata

研究成果: ジャーナルへの寄稿学術誌査読

1 被引用数 (Scopus)


We investigated pancreatic endocrine function, exocrine function and insulin resistance in 9 subjects with chronic calcifying pancreatitis (CCP). Insulin and glucagon secretory function were reduced in most of the patients, and pancreatic exocrine function was disturbed in all 9. Insulin resistance was evaluated using a euglycemic hyperinsulinemic clamp technique. Most of the patients had marked insulin resistance. The correlation between glucagon secretory function and insulin resistance was statistically significant. The results suggested that the reductions in insulin secretion and insulin resistance were observed in the early stage of impaired glucose tolerance associated with chronic pancreatitis and that the insulin resistance diminished together with the development of A cell dysfunction.

ジャーナルJournal of the Japan Diabetes Society
出版ステータス出版済み - 1999

!!!All Science Journal Classification (ASJC) codes

  • 内科学
  • 内分泌学、糖尿病および代謝内科学
  • 内分泌学


「Impaired glucose tolerance and insulin resistance in chronic calcifying pancreatitis」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。