Hydroxy-carbonate apatite (CAp) compositions containing carbonate ions from 0 to 10.9 wt% were synthesized by a wet chemical method. Infrared analysis revealed that carbonate ions were substituted both PO43- and OH- sites. The introduction of CO32- ion into the hydroxyapatite lattice led to an increase in specific surface area and surface charge density. Blood clotting properties were not affected by the contact with CAp samples. The adsorption behavior of proteins was investigated by contacting CAp with model saline containing bovine serum albumin (BSA) and β2-microglobulin (β2-MG). The selectivity against β2-MG increased with increase in the amount of carbonate ions. As surface charge density increased with increase in the amount of carbonate ions, surface charge density played an important role in selective adsorption of β2-MG, but not a sole factor.
|出版ステータス||出版済み - 12月 1 2003|
|イベント||Bioceramics: Materials and Applications IV, Proceedings - Nashville, TN, 米国|
継続期間: 4月 27 2003 → 4月 30 2003
|その他||Bioceramics: Materials and Applications IV, Proceedings|
|Period||4/27/03 → 4/30/03|
!!!All Science Journal Classification (ASJC) codes