TY - GEN
T1 - Geometrical control of a single DNA molecule translocation velocity in nanopore channels
AU - Sun, Xiaoyin
AU - Yasui, Takao
AU - Rahong, Sakon
AU - Yanagida, Takeshi
AU - Kaji, Noritada
AU - Kanai, Masaki
AU - Nagashima, Kazuki
AU - Kawai, Tomoji
AU - Baba, Yoshinobu
PY - 2014
Y1 - 2014
N2 - The geometrical control of translocation velocity for single DNA molecules in nanoscale space was studied in this paper. We fabricated the nanopore channels which have 250 μm in length, 300 nm in width and 300 nm in depth for confinement of single DNA molecules, and measurement of single DNA molecules translocation velocities. Single DNA molecules translocation velocities in nanopore channels were controlled by fabricating the different nanostructures in front of nanopore channels, such as shallow channels and nanopillars. Based on these strategies, we successfully decreased the single DNA molecules translocation velocities to 7.7 ± 0.8×10-3 cm/s in nanopore channels.
AB - The geometrical control of translocation velocity for single DNA molecules in nanoscale space was studied in this paper. We fabricated the nanopore channels which have 250 μm in length, 300 nm in width and 300 nm in depth for confinement of single DNA molecules, and measurement of single DNA molecules translocation velocities. Single DNA molecules translocation velocities in nanopore channels were controlled by fabricating the different nanostructures in front of nanopore channels, such as shallow channels and nanopillars. Based on these strategies, we successfully decreased the single DNA molecules translocation velocities to 7.7 ± 0.8×10-3 cm/s in nanopore channels.
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M3 - Conference contribution
AN - SCOPUS:84941660016
T3 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
SP - 1338
EP - 1340
BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PB - Chemical and Biological Microsystems Society
T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Y2 - 26 October 2014 through 30 October 2014
ER -