Ganoderic acids from ganoderma lucidum: Inhibitory activity of osteoclastic differentiation and structural criteria

Jie Liu; Jun Shiono; Kuniyoshi Shimizu; Ryuichiro Kondo

doi:10.1055/s-0029-1186035

Ganoderic acids from ganoderma lucidum: Inhibitory activity of osteoclastic differentiation and structural criteria

Jie Liu, Jun Shiono, Kuniyoshi Shimizu, Ryuichiro Kondo

サスティナブル資源科学

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

15 被引用数 (Scopus)

抄録

Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases. Ganoderma lucidum is known for medicinal effects such as anti-inflammatory and anti-bone resorption activities. In this study, we investigated the inhibitory effects of ganoderic acids isolated from G. lucidum on osteoclastic differentiation using RAW264 cells in vitro. A carbonyl in C7 is essential to elicit the inhibition of osteoclast differentiation.

本文言語	英語
ページ（範囲）	137-139
ページ数	3
ジャーナル	Planta medica
巻	76
号	2
DOI	https://doi.org/10.1055/s-0029-1186035
出版ステータス	出版済み - 2010

!!!All Science Journal Classification (ASJC) codes

分析化学
分子医療
薬理学
薬科学
創薬
補完代替医療
有機化学

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Ganoderic acids from ganoderma lucidum: Inhibitory activity of osteoclastic differentiation and structural criteria

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!!!All Science Journal Classification (ASJC) codes

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