Extraskeletal myxoid chondrosarcoma with rhabdoid features, with special reference to its aggressive behavior

Yumi Oshiro, Hideki Shiratsuchi, Sadafumi Tamiya, Yoshinao Oda, Satoshi Toyoshima, Masazumi Tsuneyoshi

研究成果: ジャーナルへの寄稿学術誌査読

25 被引用数 (Scopus)

抄録

The presence of rhabdoid cells has been reported in Various types of malignant neoplasms. Thirty-six cases of extraskeletal myxoid chondrosarcoma (EMC) were reviewed, and three of them revealed rhabdoid features. These cases contained cells having prominent eosinophilic globular cytoplasm, but were otherwise typical of EMC. Immunohistochemically, cytokeratin (CAM 5.2) was positive in three of 20 cases (15%), including two of the three with rhabdoid features. The rhabdoid cells were also immunostained with vimentin. The 5-year survival rate in the 26 cases with follow-up information was 73%, and the 10-year survival rate was 63%. The cases with rhabdoid features had a significantly poorer prognosis (p=0.0271). This study suggests that presence of rhabdoid features is a predictor of aggressive behavior in EMC, as it was shown to be in other mesenchymal neoplasms.

本文言語英語
ページ(範囲)145-152
ページ数8
ジャーナルInternational Journal of Surgical Pathology
8
2
DOI
出版ステータス出版済み - 4月 2000

!!!All Science Journal Classification (ASJC) codes

  • 外科
  • 解剖学
  • 病理学および法医学

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