TY - JOUR
T1 - Enhancement of disease resistance to Magnaporthe grisea in rice by accumulation of hydroxy linoleic acid
AU - Yara, Asanori
AU - Yaeno, Takashi
AU - Montillet, Jean Luc
AU - Hasegawa, Morifumi
AU - Seo, Shigemi
AU - Kusumi, Kensuke
AU - Iba, Koh
N1 - Funding Information:
We thank Prof. Hiroyuki Ohta (Tokyo Institute of Technology) for critical reading and helpful discussion. This research was supported by CREST, JST, and the Ministry of Agriculture, Forestry, and Fisheries of Japan (Rice Genome Project IP-5005) and the Japan Society of the Promotion of Science (17370019) grants.
PY - 2008/5/30
Y1 - 2008/5/30
N2 - Linoleic acid (18:2) and linolenic acid (18:3) are sources for various oxidized metabolites called oxylipins, some of which inhibit growth of fungal pathogens. In a previous study, we found disease resistance to rice blast fungus Magnaporthe grisea enhanced in 18:2-accumulating transgenic rice (F78Ri) in which the conversion from 18:2 to 18:3 was suppressed. Here, we demonstrate that 18:2-derived hydroperoxides and hydroxides (HPODEs and HODEs, respectively) inhibit growth of M. grisea more strongly than their 18:3-derived counterparts. Furthermore, in F78Ri plants, the endogenous levels of HPODEs and HODEs increased significantly, compared with wild-type plants. These results suggest that the increased accumulation of antifungal oxylipins, such as HPODEs and HODEs, causes the enhancement of disease resistance against M. grisea.
AB - Linoleic acid (18:2) and linolenic acid (18:3) are sources for various oxidized metabolites called oxylipins, some of which inhibit growth of fungal pathogens. In a previous study, we found disease resistance to rice blast fungus Magnaporthe grisea enhanced in 18:2-accumulating transgenic rice (F78Ri) in which the conversion from 18:2 to 18:3 was suppressed. Here, we demonstrate that 18:2-derived hydroperoxides and hydroxides (HPODEs and HODEs, respectively) inhibit growth of M. grisea more strongly than their 18:3-derived counterparts. Furthermore, in F78Ri plants, the endogenous levels of HPODEs and HODEs increased significantly, compared with wild-type plants. These results suggest that the increased accumulation of antifungal oxylipins, such as HPODEs and HODEs, causes the enhancement of disease resistance against M. grisea.
UR - https://www.scopus.com/pages/publications/42249098411
UR - https://www.scopus.com/pages/publications/42249098411#tab=citedBy
U2 - 10.1016/j.bbrc.2008.03.083
DO - 10.1016/j.bbrc.2008.03.083
M3 - Article
C2 - 18373976
AN - SCOPUS:42249098411
SN - 0006-291X
VL - 370
SP - 344
EP - 347
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -