Effect of three-dimensional electric field and heat conduction to electrodes on the temperature rise during irreversible electroporation

Seiji Nomura, Kosaku Kurata, Hiroshi Takamatsu

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

4 被引用数 (Scopus)

抄録

The irreversible electroporation (IRE) is a novel method to ablate abnormal cells by applying a high voltage between two electrodes that are stuck into abnormal tissues. One of the advantages of the IRE is that the extracellular matrix (ECM) may be kept intact, which is favorable for healing. For a successful IRE, it is therefore important to avoid thermal damage of ECM resulted from the Joule heating within the tissue. A three-dimensional (3-D) analysis was conducted in this study to predict temperature rise during the IRE. The equation of electric field and the heat conduction equation were solved numerically by a finite element method. It was clarified that the highest temperature rise occurred at the base of electrodes adjacent to the insulated surface. The result was significantly different from a two-dimensional (2-D) analysis due to end effects, suggesting that the 3-D analysis is required to determine the optimal condition.

本文言語英語
ホスト出版物のタイトルASME/JSME 2011 8th Thermal Engineering Joint Conference, AJTEC 2011
出版社American Society of Mechanical Engineers
ISBN(印刷版)9780791838921
DOI
出版ステータス出版済み - 2011
イベントASME/JSME 2011 8th Thermal Engineering Joint Conference, AJTEC 2011 - Honolulu, HI, 米国
継続期間: 3月 13 20113月 17 2011

出版物シリーズ

名前ASME/JSME 2011 8th Thermal Engineering Joint Conference, AJTEC 2011

その他

その他ASME/JSME 2011 8th Thermal Engineering Joint Conference, AJTEC 2011
国/地域米国
CityHonolulu, HI
Period3/13/113/17/11

!!!All Science Journal Classification (ASJC) codes

  • エネルギー工学および電力技術

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