Diversity in guanosine 3′,5′-bisdiphosphate (ppGpp) sensitivity among guanylate kinases of bacteria and plants

Yuhta Nomura; Atsushi Izumi; Yoshinori Fukunaga; Kensuke Kusumi; Koh Iba; Seiya Watanabe; Yoichi Nakahira; Andreas P.M. Weber; Akira Nozawa; Yuzuru Tozawa

doi:10.1074/jbc.M113.534768

Diversity in guanosine 3′,5′-bisdiphosphate (ppGpp) sensitivity among guanylate kinases of bacteria and plants

Yuhta Nomura, Atsushi Izumi, Yoshinori Fukunaga, Kensuke Kusumi, Koh Iba, Seiya Watanabe, Yoichi Nakahira, Andreas P.M. Weber, Akira Nozawa, Yuzuru Tozawa

情報生物学

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

28 被引用数 (Scopus)

抄録

Background: The ppGpp signaling system is operative in plant chloroplasts and bacteria. Results: Chloroplast and cytosolic guanylate kinases (GKs) of plants are sensitive and insensitive to ppGpp, respectively, whereas bacterial GKs show diversity in ppGpp sensitivity. Conclusion: GTP biosynthesis in chloroplasts is controlled by ppGpp. Significance: Identification of the targets of ppGpp should provide insight into biological processes regulated by this nucleotide.

本文言語	英語
ページ（範囲）	15631-15641
ページ数	11
ジャーナル	Journal of Biological Chemistry
巻	289
号	22
DOI	https://doi.org/10.1074/jbc.M113.534768
出版ステータス	出版済み - 5月 30 2014

!!!All Science Journal Classification (ASJC) codes

生化学
分子生物学
細胞生物学

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title = "Diversity in guanosine 3′,5′-bisdiphosphate (ppGpp) sensitivity among guanylate kinases of bacteria and plants",

abstract = "Background: The ppGpp signaling system is operative in plant chloroplasts and bacteria. Results: Chloroplast and cytosolic guanylate kinases (GKs) of plants are sensitive and insensitive to ppGpp, respectively, whereas bacterial GKs show diversity in ppGpp sensitivity. Conclusion: GTP biosynthesis in chloroplasts is controlled by ppGpp. Significance: Identification of the targets of ppGpp should provide insight into biological processes regulated by this nucleotide.",

author = "Yuhta Nomura and Atsushi Izumi and Yoshinori Fukunaga and Kensuke Kusumi and Koh Iba and Seiya Watanabe and Yoichi Nakahira and Weber, {Andreas P.M.} and Akira Nozawa and Yuzuru Tozawa",

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doi = "10.1074/jbc.M113.534768",

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T1 - Diversity in guanosine 3′,5′-bisdiphosphate (ppGpp) sensitivity among guanylate kinases of bacteria and plants

AU - Nomura, Yuhta

AU - Izumi, Atsushi

AU - Fukunaga, Yoshinori

AU - Kusumi, Kensuke

AU - Iba, Koh

AU - Watanabe, Seiya

AU - Nakahira, Yoichi

AU - Weber, Andreas P.M.

AU - Nozawa, Akira

AU - Tozawa, Yuzuru

PY - 2014/5/30

Y1 - 2014/5/30

N2 - Background: The ppGpp signaling system is operative in plant chloroplasts and bacteria. Results: Chloroplast and cytosolic guanylate kinases (GKs) of plants are sensitive and insensitive to ppGpp, respectively, whereas bacterial GKs show diversity in ppGpp sensitivity. Conclusion: GTP biosynthesis in chloroplasts is controlled by ppGpp. Significance: Identification of the targets of ppGpp should provide insight into biological processes regulated by this nucleotide.

AB - Background: The ppGpp signaling system is operative in plant chloroplasts and bacteria. Results: Chloroplast and cytosolic guanylate kinases (GKs) of plants are sensitive and insensitive to ppGpp, respectively, whereas bacterial GKs show diversity in ppGpp sensitivity. Conclusion: GTP biosynthesis in chloroplasts is controlled by ppGpp. Significance: Identification of the targets of ppGpp should provide insight into biological processes regulated by this nucleotide.

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Diversity in guanosine 3′,5′-bisdiphosphate (ppGpp) sensitivity among guanylate kinases of bacteria and plants

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!!!All Science Journal Classification (ASJC) codes

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