Development of an assay of seven biochemical items, HbA1c, and hematocrit using a small amount of blood collected from the fingertip

Sugimoto Shinya, Akimoto Masaru, Hayakawa Akira, Hokazono Eisaku, Osawa Susumu

研究成果: ジャーナルへの寄稿学術誌査読

11 被引用数 (Scopus)

抄録

Background: Lifestyle-related diseases in Japan account for 30% of the entire medical expenditure of the country and cause 60% of all deaths. For the prevention of lifestyle-related diseases, medical examination by laboratory tests on metabolic syndrome is important. Methods: To undertake examination by collection of blood from a fingertip, we developed the "Well Kit". About 65 μl of blood collected from a fingertip was diluted with buffer solution, which contained two internal standard materials. The kit also separated corpuscles and diluted plasma with a special filter. It measured the obtained diluted plasma using the JCA-BM2250. Results: This measurement system was evaluated for the quantitative analysis of 8 items. The uncertainties of tested items of this measurement system were 1.7% to 6.4%. The coefficients of correlation of all tested items between this measurement value and the venous plasma sample value were 0.876-0.991, and hematocrit was 0.958. Conclusions: This system for testing blood collected from a fingertip is simple to use and can be applied in testing for metabolic syndrome. In addition, this testing system is useful in the medical examination of the personal healthcare and inhabitants.

本文言語英語
ページ(範囲)192-197
ページ数6
ジャーナルClinica Chimica Acta
413
1-2
DOI
出版ステータス出版済み - 1月 18 2012

!!!All Science Journal Classification (ASJC) codes

  • 生化学
  • 臨床生化学
  • 生化学、医学

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