Development of a uniaxial mechanical loading device to evaluate osteogenic differentiation of stem cells seeded on a scaffold material

Masakazu Yamada, Takahisa Anada, Taisuke Masuda, Teruko Takano-Yamamoto, Osamu Suzuki

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

抄録

The present study was designed to investigate the effect of the uniaxial mechanical strain on the proliferation and differentiation of mouse mesenchymal stem D1 cells seeded into the octacalcium phosphate (OCP)/ Gelatin (Gel) composite in vitro. The mechanical stimulation with a uniaxial loading device was analyzed by finite element analysis in order to elucidate quantitatively the effect of the strain on D1 cells seeded into the OCP/Gel composite. The results suggest that osteoblastic differentiation of D1 cells is suppressed by overloading of the compressive strain, but promoted if suitable mechanical stress is provided.

本文言語英語
ホスト出版物のタイトル2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
出版社Institute of Electrical and Electronics Engineers Inc.
ISBN(電子版)9781479966783
DOI
出版ステータス出版済み - 3月 21 2016
外部発表はい
イベントInternational Symposium on Micro-NanoMechatronics and Human Science, MHS 2015 - Nagoya, 日本
継続期間: 11月 23 201511月 25 2015

出版物シリーズ

名前2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015

その他

その他International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
国/地域日本
CityNagoya
Period11/23/1511/25/15

!!!All Science Journal Classification (ASJC) codes

  • 生体医工学
  • 電子工学および電気工学
  • バイオテクノロジー
  • 教育

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