TY - GEN
T1 - Coulometric detection of an analyte in a liquid plug formed in a microflow channel
AU - Sassa, F.
AU - Laghzali, H.
AU - Fukuda, J.
AU - Suzuki, H.
PY - 2009/12/11
Y1 - 2009/12/11
N2 - Applicability of coulometric detection was tested for the analysis of an analyte in a liquid plug confined in a PDMS microflow channel. A plug prepared in the flow channel was placed on a three-electrode system and hydrogen peroxide was detected. With plugs of a small volume, the depletion of the analyte was rapid, making reproducible amperometric detection difficult particularly when the flow channel was shallow. On the other hand, coulometric detection showed a clear relationship between the generated charge and the concentration. However, when the volume of the plug was large, only a part of the analyte was used for detection, suggesting the possibility to improve the detection sensitivity further. The device was also tested in the detection of L-glutamate.
AB - Applicability of coulometric detection was tested for the analysis of an analyte in a liquid plug confined in a PDMS microflow channel. A plug prepared in the flow channel was placed on a three-electrode system and hydrogen peroxide was detected. With plugs of a small volume, the depletion of the analyte was rapid, making reproducible amperometric detection difficult particularly when the flow channel was shallow. On the other hand, coulometric detection showed a clear relationship between the generated charge and the concentration. However, when the volume of the plug was large, only a part of the analyte was used for detection, suggesting the possibility to improve the detection sensitivity further. The device was also tested in the detection of L-glutamate.
UR - http://www.scopus.com/inward/record.url?scp=71449125309&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=71449125309&partnerID=8YFLogxK
U2 - 10.1109/SENSOR.2009.5285975
DO - 10.1109/SENSOR.2009.5285975
M3 - Conference contribution
AN - SCOPUS:71449125309
SN - 9781424441938
T3 - TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
SP - 955
EP - 958
BT - TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
T2 - TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems
Y2 - 21 June 2009 through 25 June 2009
ER -