TY - GEN
T1 - Control of DNA translocation velocities for nanopore-based DNA sequencing
AU - Sun, Xiaoyin
AU - Yasui, Takao
AU - Rahong, Sakon
AU - Yanagida, Takeshi
AU - Kaji, Noritada
AU - Kanai, Masaki
AU - Nagashima, Kazuki
AU - Kawai, Tomoji
AU - Baba, Yoshinobu
PY - 2013
Y1 - 2013
N2 - Reducing translocation velocity of DNA molecules in a nanopore is an urgent issue for rapid single identification. Here we fabricated a nanopore-channel, which has 300 × 300nm (width and depth) dimensions for electrophoretically driven transport of single DNA molecule, and decreased the single DNA molecule's translocation velocity by changing length of the nanopore-channels or electric fields. We obtained a 180 kbp/s translocation velocity for 10 kbp DNA through the 250 μm long nanopore-channel by applying 3 V.
AB - Reducing translocation velocity of DNA molecules in a nanopore is an urgent issue for rapid single identification. Here we fabricated a nanopore-channel, which has 300 × 300nm (width and depth) dimensions for electrophoretically driven transport of single DNA molecule, and decreased the single DNA molecule's translocation velocity by changing length of the nanopore-channels or electric fields. We obtained a 180 kbp/s translocation velocity for 10 kbp DNA through the 250 μm long nanopore-channel by applying 3 V.
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M3 - Conference contribution
AN - SCOPUS:84907322467
SN - 9781632666246
T3 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
SP - 1117
EP - 1119
BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PB - Chemical and Biological Microsystems Society
T2 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Y2 - 27 October 2013 through 31 October 2013
ER -