TY - JOUR
T1 - Conformational analysis of meropenem and desmethyl meropenem
T2 - The effect of 1β-methyl group on carbapenem antibiotics
AU - Igarashi, Jun Etsu
AU - Nishimura, Tamiki
AU - Sasaki, Akira
AU - Sunagawa, Makoto
PY - 1996/8/20
Y1 - 1996/8/20
N2 - The conformations of meropenem and desmethyl meropenem have been studied using MM calculations and 1H NMR experiments. It was found that the preferred conformation of meropenem was relatively linear compared with desmethyl meropenem in aqueous solution.
AB - The conformations of meropenem and desmethyl meropenem have been studied using MM calculations and 1H NMR experiments. It was found that the preferred conformation of meropenem was relatively linear compared with desmethyl meropenem in aqueous solution.
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U2 - 10.1016/0960-894X(96)00341-1
DO - 10.1016/0960-894X(96)00341-1
M3 - Article
AN - SCOPUS:0030594997
SN - 0960-894X
VL - 6
SP - 1881
EP - 1886
JO - Bioorganic and Medicinal Chemistry Letters
JF - Bioorganic and Medicinal Chemistry Letters
IS - 16
ER -