Computerized three-dimensional reconstruction of human embryos and their organs using the "NIH image" software

Three-dimensional structures of human embryos and their internal organs were reconstructed on a CRT from their serial histological sections using a free computer software system "NIH Image." It was possible to rotate the computer images on CRT and to make cut models on any desired plane. In addition, various developmental changes could be animated by artificial "morphing" between the models at different stages. Computer graphic modeling should be of great value in the study of normal and abnormal morphogenesis. The "NIH Image" software is freely available via computer networks and has a lot of advantages over previously developed software programs used for three-dimensional reconstruction.