TY - JOUR
T1 - Colorectal endoscopic submucosal dissection using novel articulating devices
T2 - a comparative study in a live porcine model
AU - Okamoto, Yasuharu
AU - Nakadate, Ryu
AU - Nakamura, Shotaro
AU - Arata, Jumpei
AU - Oguri, Susumu
AU - Moriyama, Tomohiko
AU - Esaki, Motohiro
AU - Iwasa, Tsutomu
AU - Ohuchida, Kenoki
AU - Akahoshi, Tomohiko
AU - Ikeda, Tetsuo
AU - Kitazono, Takanari
AU - Hashizume, Makoto
N1 - Funding Information:
Disclosures Drs. Okamoto, Nakadate, Nakamura, Arata, Ohuchida, and Hashizume have received research funding from Hogy Medical Co. Ltd., Japan. Drs. Oguri, Moriyama, Esaki, Iwasa, Akahoshi, Ikeda and Kitazono have no conflicts of interest or financial ties to disclose.
Publisher Copyright:
© 2018, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2019/2/15
Y1 - 2019/2/15
N2 - Background and aims: Colonic endoscopic submucosal dissection (ESD) is time-consuming and bears a high risk of perforation. The aim of the present study was to compare the safety and efficacy between novel articulating devices and conventional ESD in live porcine colon models. Methods: Thirty ESDs in ten pigs were carried out at three different locations (15, 25, and 35 cm from the anus) by the conventional method (n = 15) and by the new method (n = 15). Procedure times, adverse events (perforation, bleeding), and damage to the muscular layer were recorded, and the ESD time per unit area of the specimens was calculated. Results: The perforation rate using the conventional method was 6.7% (1/15), whereas that using the new method was 0.0%. The number of sites of muscular damage was significantly lower in the new than conventional method (6 vs. 37, respectively; P = 0.024). The mean procedure time was significantly shorter in the new than conventional method (4.6 ± 2.0 vs. 7.0 ± 4.1 min/cm 2 , respectively; P = 0.042). Conclusions: Use of the new ESD method allows for reduced adverse events and a shortened resection time.
AB - Background and aims: Colonic endoscopic submucosal dissection (ESD) is time-consuming and bears a high risk of perforation. The aim of the present study was to compare the safety and efficacy between novel articulating devices and conventional ESD in live porcine colon models. Methods: Thirty ESDs in ten pigs were carried out at three different locations (15, 25, and 35 cm from the anus) by the conventional method (n = 15) and by the new method (n = 15). Procedure times, adverse events (perforation, bleeding), and damage to the muscular layer were recorded, and the ESD time per unit area of the specimens was calculated. Results: The perforation rate using the conventional method was 6.7% (1/15), whereas that using the new method was 0.0%. The number of sites of muscular damage was significantly lower in the new than conventional method (6 vs. 37, respectively; P = 0.024). The mean procedure time was significantly shorter in the new than conventional method (4.6 ± 2.0 vs. 7.0 ± 4.1 min/cm 2 , respectively; P = 0.042). Conclusions: Use of the new ESD method allows for reduced adverse events and a shortened resection time.
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U2 - 10.1007/s00464-018-6408-5
DO - 10.1007/s00464-018-6408-5
M3 - Article
C2 - 30187199
AN - SCOPUS:85053277559
SN - 0930-2794
VL - 33
SP - 651
EP - 657
JO - Surgical endoscopy
JF - Surgical endoscopy
IS - 2
ER -