Clinical features of red blood cell-coated intraocular lens after breakthrough vitreous hemorrhage secondary to neovascular age-related macular degeneration

Hyeong Min Kim, Yusuke Murakami, Se Joon Woo

研究成果: ジャーナルへの寄稿学術誌査読

抄録

Purpose: To investigate the incidence and clinical features of red blood cell (RBC)-coated intraocular lens (IOL) in breakthrough vitreous hemorrhage (VH) with subretinal hemorrhage (SRH) secondary to neovascular age-related macular degeneration (nAMD). Setting: Seoul National University Bundang Hospital, Seongnam, Korea. Design: Retrospective cohort analysis. Methods: A total of 30 patients diagnosed as breakthrough VH with SRH in nAMD who underwent pars plana vitrectomy were included in this study. Demographics and clinical characteristics of the subjects, visual acuities, and SRH sizes measured as disc diameters were analyzed. The correlation analysis between SRH size and absorption duration of RBC-coated IOL were performed. Results: Out of 30 eyes in 30 patients, RBC-coated IOLs were observed in 11 patients (37%). Appearance of RBC-coated IOLs was noted 1 month postoperatively, and the mean duration of SRH absorption was 8.6 ± 2.6 months. SRH sizes were significantly different between eyes with RBC-coated IOL and clear IOL (62.8 ± 20.7 vs 27.4 ± 14.2, P <.001). There was definite correlation between SRH size and absorption duration of RBC-coated IOL (correlation coefficient 0.899, P <.001, R2= 0.831). There were no statistically significant differences according to age, sex, laterality, underlying medical conditions, preoperative lens status, history of antivascular endothelial growth factor treatment, and visual acuities. The degenerated RBC on the surface of IOL was confirmed by electron and light microscopy. Conclusions: RBC-coated IOL could develop after vitrectomy surgery for breakthrough VH with massive SRH secondary to nAMD, and it can be confused with IOL opacification. Because it spontaneously disappears gradually, observation without IOL removal is warranted.

本文言語英語
ページ(範囲)892-897
ページ数6
ジャーナルJournal of Cataract and Refractive Surgery
47
7
DOI
出版ステータス出版済み - 7月 1 2021

!!!All Science Journal Classification (ASJC) codes

  • 外科
  • 眼科学
  • 感覚系

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