Chronic periodontitis with multiple risk factor syndrome: a case report.

Masayuki Shimoe, Tadashi Yamamoto, Yoshihiro Iwamoto, Nobuyuki Shiomi, Hiroshi Maeda, Fusanori Nishimura, Shogo Takashiba

研究成果: ジャーナルへの寄稿学術誌査読

5 被引用数 (Scopus)

抄録

Multiple risk factor syndrome is a clustering of cardiovascular risk factors, such as diabetes, dyslipidemia, hypertension, and obesity associated epidemiologically with insulin resistance. This report describes the clinical course of a patient suffering from severe periodontitis with multiple risk factor syndrome, and discusses the association between periodontal infection and systemic health. The patient had a history of type 2 diabetes, dyslipidemia, and hypertension for over 10 years. At baseline, her hemoglobin A1 c was 8.1%. However, she had no diabetic complications except periodontitis. The IgG antibody titers against Porphyromonas gingivalis FDC 381 and SU63 were elevated above the mean of healthy subjects +2 standard deviations. Intensive periodontal treatment, including periodontal surgery, was performed to reduce periodontal infection and bacteremia. Her systemic and periodontal conditions were evaluated longitudinally for 10 years. Following periodontal treatment, antibody titers against Porphyromonas gingivalis and hemoglobin A1c values were significantly improved. The other clinical data and medication for her systemic condition also remained stable during supportive periodontal therapy. However, she developed myocardial infarction, and showed continuous deterioration of hemoglobin A1 c level and periodontitis. The long-term clustering of risk factors, such as diabetes, dyslipidemia, hypertension, and periodontitis, are associated with the development of myocardial infarction. Treatment of systemic conditions in combination with comprehensive periodontal treatment is important in management of patients with multiple risk factor syndrome.

本文言語英語
ページ(範囲)40-47
ページ数8
ジャーナルJournal of the International Academy of Periodontology
13
2
出版ステータス出版済み - 7月 2011
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 医学一般

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