Characterization of a novel superoxide dismutase in Nilaparvata lugens

Kohji Yamamoto, Misuzu Yamaguchi

研究成果: ジャーナルへの寄稿学術誌査読

2 被引用数 (Scopus)


The brown planthopper (Nilaparvata lugens) is a major agricultural pest of rice crops. Analysis of the enzymes produced by N. lugens is important to develop pest-control methods. Superoxide dismutase (SOD) is a detoxification enzyme that catalyzes the conversion of superoxide anions (reactive oxygen species) into oxygen and hydrogen peroxide. As there have been no reports on SOD in N. lugens, in this study, we characterized a new SOD in the brown planthopper, nlSOD1. Amino acid sequence and phylogenetic analyses revealed that nlSOD1 is a member of the Cu/Zn-SOD family. Recombinant nlSOD1, when overexpressed in Escherichia coli, catalyzes the dismutation of superoxide radicals into molecular O2 and H2O2. Exposure to various insecticides induced nlSOD1 messenger RNA expression. These results indicate that nlSOD1 may contribute to the insecticide resistance of N. lugens. The findings of this study may assist in the development of novel methods to control the population of N. lugens.

ジャーナルArchives of insect biochemistry and physiology
出版ステータス出版済み - 2月 2022

!!!All Science Journal Classification (ASJC) codes

  • 生化学
  • 生理学
  • 昆虫科学


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