Cardiovascular protective action of Rho-kinase inhibitors

Yoshitaka Hirooka

研究成果: ジャーナルへの寄稿総説査読

抄録

The Rho/Rho-kinase pathway plays an important role in pathophysiology and formation of hypertensive vascular diseases. This pathway contributes to both increased vascular resistance and atherosclerotic changes. The latter includes inflammatory and proliferative changes. In patients with hypertension, inhibition of Rho-kinase has been shown to decrease the increased vascular resistance. Therefore, Rho-kinase will be a new therapeutic target for hypertension and hypertensive vascular diseases. Thus, Rho-kinase inhibitors may have a cardioprotective action.

本文言語英語
ページ(範囲)161-171
ページ数11
ジャーナルNippon rinsho. Japanese journal of clinical medicine
62
1
出版ステータス出版済み - 1月 2004
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 医学一般

フィンガープリント

「Cardiovascular protective action of Rho-kinase inhibitors」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル