Biosynthetic studies of the tetramic acid antibiotic trichosetin

Eufrocinio C. Marfori; Takeshi Bamba; Shin Ichiro Kajiyama; Ei Ichiro Fukusaki; Akio Kobayashi

doi:10.1016/S0040-4020(02)00689-0

Biosynthetic studies of the tetramic acid antibiotic trichosetin

Eufrocinio C. Marfori, Takeshi Bamba, Shin Ichiro Kajiyama, Ei Ichiro Fukusaki, Akio Kobayashi

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

28 被引用数 (Scopus)

抄録

A feeding experiment with ¹³C-labeled precursors was conducted in the dual cultures of Trichoderma harzianum H14 and Catharanthus roseus callus to determine the biosynthetic origin of the carbon atoms in trichosetin. Results showed that trichosetin originated from two separate biogenetic units. One unit is an octaketide intermediate directly derived from eight intact acetate units joined in a head-to-tail fashion of a polyketide pathway. The other unit is serine.

本文言語	英語
ページ（範囲）	6655-6658
ページ数	4
ジャーナル	Tetrahedron
巻	58
号	33
DOI	https://doi.org/10.1016/S0040-4020(02)00689-0
出版ステータス	出版済み - 8月 12 2002
外部発表	はい

!!!All Science Journal Classification (ASJC) codes

生化学
創薬
有機化学

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10.1016/S0040-4020(02)00689-0

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title = "Biosynthetic studies of the tetramic acid antibiotic trichosetin",

abstract = "A feeding experiment with 13C-labeled precursors was conducted in the dual cultures of Trichoderma harzianum H14 and Catharanthus roseus callus to determine the biosynthetic origin of the carbon atoms in trichosetin. Results showed that trichosetin originated from two separate biogenetic units. One unit is an octaketide intermediate directly derived from eight intact acetate units joined in a head-to-tail fashion of a polyketide pathway. The other unit is serine.",

author = "Marfori, {Eufrocinio C.} and Takeshi Bamba and Kajiyama, {Shin Ichiro} and Fukusaki, {Ei Ichiro} and Akio Kobayashi",

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AU - Bamba, Takeshi

AU - Kajiyama, Shin Ichiro

AU - Fukusaki, Ei Ichiro

AU - Kobayashi, Akio

PY - 2002/8/12

Y1 - 2002/8/12

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AB - A feeding experiment with 13C-labeled precursors was conducted in the dual cultures of Trichoderma harzianum H14 and Catharanthus roseus callus to determine the biosynthetic origin of the carbon atoms in trichosetin. Results showed that trichosetin originated from two separate biogenetic units. One unit is an octaketide intermediate directly derived from eight intact acetate units joined in a head-to-tail fashion of a polyketide pathway. The other unit is serine.

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JO - Tetrahedron

JF - Tetrahedron

IS - 33

ER -

Biosynthetic studies of the tetramic acid antibiotic trichosetin

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!!!All Science Journal Classification (ASJC) codes

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