TY - GEN
T1 - Biodegradation behavior of segmented polyurethanes prepared from amino acid-based diisocyanate
AU - Takahara, Atsushi
AU - Hadano, Michiko
AU - Yamaguchi, Tomohiro
AU - Otsuka, Hideyuki
AU - Kidoaki, Satoru
AU - Matsuda, Takehisa
AU - Aoi, Keigo
AU - Sasaki, Sono
PY - 2005
Y1 - 2005
N2 - Segmented poly(urethaneurea)s (SPUUs) were synthesized from lysine-based diisocyanate (LDI), polycaprolactone diol (PCL) and 1,4-butanediamine (BDA). The hard segment fraction was changed in order to control the mechanical properties and the degradability. The physicochemical and structural characterizations of SPUUs were carried out by infrared spectroscopy and differential scanning calorimetry (DSC), temperature dependence of dynamic viscoelasticity and small-angle X-ray scattering (SAXS). DSC showed that the glass transition temperature (Tg) of BDA-based hard segment is located at ca.373K. DSC and dynamic viscoelastic measurements revealed that Tg of soft segment increased with an increase in hard segment fraction. SAXS of SPUUs revealed the molecular aggregation states of hard and soft segments. Furthermore, the degradation behavior was investigated by exposing the polymers to a buffer solution at 310 K (pH=7.6) and activated sludge. The higher degradation rate in activated sludge compared with that in a buffer solution suggested the biodegrability of SPUUs. Finally, an electrospray deposition method was used to fabricate biodegradable SPUU nanofibers.
AB - Segmented poly(urethaneurea)s (SPUUs) were synthesized from lysine-based diisocyanate (LDI), polycaprolactone diol (PCL) and 1,4-butanediamine (BDA). The hard segment fraction was changed in order to control the mechanical properties and the degradability. The physicochemical and structural characterizations of SPUUs were carried out by infrared spectroscopy and differential scanning calorimetry (DSC), temperature dependence of dynamic viscoelasticity and small-angle X-ray scattering (SAXS). DSC showed that the glass transition temperature (Tg) of BDA-based hard segment is located at ca.373K. DSC and dynamic viscoelastic measurements revealed that Tg of soft segment increased with an increase in hard segment fraction. SAXS of SPUUs revealed the molecular aggregation states of hard and soft segments. Furthermore, the degradation behavior was investigated by exposing the polymers to a buffer solution at 310 K (pH=7.6) and activated sludge. The higher degradation rate in activated sludge compared with that in a buffer solution suggested the biodegrability of SPUUs. Finally, an electrospray deposition method was used to fabricate biodegradable SPUU nanofibers.
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M3 - Conference contribution
AN - SCOPUS:84902656638
SN - 7502577173
SN - 9787502577179
T3 - "New Century, New Materials and New Life" - Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005
SP - 897
EP - 901
BT - "New Century, New Materials and New Life" - Proceedings of 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005
PB - China Press
T2 - 2005 International Conference on Advanced Fibers and Polymer Materials, ICAFPM 2005
Y2 - 19 October 2005 through 21 October 2005
ER -